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Diabetes type 1 and type 2 discussion
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TOPIC: Diabetes Types 1 and 2 Inclined Bed Therapy Trial Pilot Study in Phonpei Island

Diabetes Types 1 and 2 Inclined Bed Therapy Trial Pilot Study in Phonpei Island 2 months 2 weeks ago #1409

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Diabetes Study needs 100 or more people with diabetes who will sleep on a five degree head end up angle for a 6 months with a view to continuing after this period.

A successful pilot study conducted on Phonpei Island, by Doctors, where diabetes has reached unprecedented levels, succeeded in lowering blood glucose significantly.
Pohnpei Diabetes study: Ponpei Diabetes Pilot Studyinclinedbedtherapy.com/research/diabetes/16-ibt-diabetes-study


If you notice higher blood sugar levels in the mornings when sleeping on your unmodified bed, commonly known as Dawn Phenomenon or Liver Dump. I believe we are looking at a solution that will help reduce glucose levels during the night and over several months, will significantly change those important readings towards more normal levels.


Please keep a journal on your computer for taking notes of all changes and for providing feedback on diabetes associated and unrelated changes in the following list:

1 Blood sugar / glucose levels

2 Weight Change

3 General Health

4 leg ulcers / pressure sores

5 Circulation in extremities (toes and fingers)

6 Body temperature and hands / feet

7 Finger and toe nails quality, strength

8 Skin tone complexion

9 Balance in morning

10 Sleep quality

11 Breathing, Sinuses Respiratory

12 Blood pressure

13 Hair colour texture, strength

14 Pain, aches, painful joints, back pain, gout etc.

15 Headaches, migraine

16 Vision / eyesight / glaucoma

17 Prognosis

18 Varicose veins, haemorrhoids,

19 Oedema / Edema / Fluid retention

20 Nocturia. Frequency of night time urination

21 Bladder infections Urinary tract infections

22 Renal function

23 Bowel / bladder function / incontinence

24 Mobility Walking Standing Movement


More common types of diabetes that we are hoping to study in the IBT trial

Type 1 diabetes Pancreas not functioning common in children.
Type 2 diabetes Pancreas functioning to some degree common in adults.
Gestational diabetes Associated with pregnancy.
Double diabetes Insulin Resistant
Steroid induced Diabetes Type 2 and 1 caused by corticosteroids.
Juvenile diabetes Young onset diabetes

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Diabetes Types 1 and 2 Inclined Bed Therapy Trial Microgravity Dawn Phenomenon 2 months 2 weeks ago #1410

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Inclined Bed Therapy makes use of gravity while we sleep! It has already been shown to reduce blood sugar levels significantly in a trial, conducted by doctors on the Island of Pohnpei, where obesity diabetes is out of control, since the introduction of the American diet.

While the Pohnpei pilot study was small, more people are coming forward to support these significant results with testimonials and case histories that I know of personally.

Dawn Phenomenon or (Liver Dump)

I have been researching diabetes in relation to flat bed rest and already seeing evidence that the pancreas does not function normally while sleeping.
In fact, there is a common problem in diabetes, where blood sugar spikes at high levels on awakening, even if food intake is restricted, it appears to remain high in the mornings; hence it's labelled as Dawn Phenomenon or Liver Dump.
It is a common belief that the increase in glucose evident in the morning blood tests is caused by an overburdening release of glucose into the blood or by the failure of our body to make use of it.

This applies to insulin dependent and non-insulin dependent alike.

Interestingly, non-diabetics experience similar early morning spikes in glucose according to a study. Demonstration of a Dawn Phenomenon in Normal Human Volunteers

Geremia B Bolli, Pierpaolo De Feo, Salvatore De Cosmo, Gabriele Perriello, Mariarosa M Ventura, Filippo Calcinaro, Claudio Lolli, Peter Campbell, Paolo Brunetti and John E Gerich

diabetes.diabetesjournals.org/content/33/12/1150.short

Clearly, there's something amiss with a so called good nights sleep.

Renal function is also affected by being in the horizontal position for hours while we sleep. The density of urine decreases in horizontal bed rest. This was tested with a simple hydrometer, which suggests dissolved solutes continue to circulate in the blood, including glucose and are effectively stored in the blood, rather than being excreted along with the urine, which is itself blood with out the cells present.

It is perfectly logical to assume that if we avoid horizontal bed rest, or indeed head down bed rest, as used by NASA to reproduce the harmful and damaging effects of space travel on astronauts, who incidentally suffer from pancreatic changes, inducing diabetes symptoms and problems including significant changes in insulin release and its functions.

"Nutritional Modulation of Pancreatic Endocrine Function in Microgravity
Principal Investigator:
Brian Tobin, Ph.D.


Organization:
Mercer University School of Medicine

The weightless environment disrupts the body’s normal use and production of insulin, which could relate to muscle atrophy. Dr. Brian Tobin is exploring whether dietary supplements of protein (amino acids) will enhance and normalize insulin secretion and decrease muscle atrophy. This research will lead to ways to keep insulin uptake at normal levels in astronauts in space and in diabetic patients on Earth."

"Ground-based and in-flight investigations illustrate changes in insulin, glucose and amino acid metabolism in space flight. These observations may relate to altered pancreatic endocrine function which is insufficient to meet the needs of microgravity-induced insulin resistance and altered amino-acid metabolism. The changes observed include decreased glucose tolerance, increased circulating insulin and increased reliance upon glucose in muscles. The metabolic meliu resembles an insulin-resistant syndrome, accompanied by a compensatory increase in pancreatic insulin secretion. However, the increase in insulin secretion is insufficient to ameliorate muscle atrophy. The increased insulin secretion is well correlated to muscle atrophy in space flight. The influence of these changes upon the loss of muscle mass and general endocrine metabolic state are not well established"

nsbri.org/researches/nutritional-modulat...ion-in-microgravity/

Inclined Bed Therapy is joining all of the dots!

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Diabetes Types 1 and 2 Lets Do Something Differently! 2 months 2 weeks ago #1411

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"The future of the NHS is at risk because the cost of treating diabetes could hit £17 billion by 2035, health experts have warned.

"According to Public Health England there are currently 4.5 million people in the UK who have diabetes, mainly type 2, but that could rise to 5 million if obesity is not tackled.

The current cost of treating diabetes is £10 billion a year which is nearly 10 per cent of the health service’s entire budget.

The national clinical director for obesity and diabetes at NHS England Professor Jonathan Valabhji said: “We need to stem the tide otherwise we could see [a] crisis and there are issues of sustainability for the NHS if we do nothing differently.” diabetestimes.co.uk/diabetes-nhs-costs-could-hit-17-billion/

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Healthy Adults Induced Impared Glucose Tolerance 21 days of bed rest 2 months 1 week ago #1412

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How Fast Is Recovery of Impaired Glucose Tolerance after 21-Day Bed Rest (NUC Study) in Healthy Adults?
Martina Heer, 1 , 2 ,* Natalie Baecker, 1 , 3 Stephan Wnendt, 4 Annelie Fischer, 2 Gianni Biolo, 5 and Petra Frings-Meuthen 3
Author information ► Article notes ► Copyright and License information ►
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Abstract
Aim. We hypothesized that 4 days of normal daily activity after 21 days of experimental bed rest (BR) will not reverse BR induced impaired glucose tolerance. Design. Glucose tolerance of seven male, healthy, untrained test subjects (age: 27.6 (3.3) years (mean (SD)); body mass: 78.6 (6.4)kg; height: 1.81 (0.04)m; VO2 max: 39.5 (5.4)ml/kg body mass/min) was studied. They stayed twice in the metabolic ward (crossover design), 21 days in bed and 7 days before and after BR each. Oral glucose tolerance tests were applied before, on day 21 of BR, and 5 and 14 days after BR. Results. On day 21 of BR, AUC120min of glucose concentration was increased by 28.8 (5.2)% and AUC120min of insulin by 35.9 (10.2)% (glucose: P < 0.001; insulin: P = 0.02). Fourteen days after BR, AUC120min of serum insulin concentrations returned to pre-bed-rest concentrations (P = 0.352) and AUC120min of glucose was still higher (P = 0.038). Insulin resistance did not change, but sensitivity index was reduced during BR (P = 0.005). Conclusion. Four days of light physical workload does not compensate inactivity induced impaired glucose tolerance. An individually tailored and intensified training regime is mandatory in patients being in bed rest to get back to normal glucose metabolism in a reasonable time frame.

europepmc.org/articles/PMC3972841

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